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Immune challenge induces N-terminal cleavage of the Drosophila serpin Necrotic
The Drosophila Necrotic protein is a serine proteinase inhibitor, which regulates the Toll-mediated innate immune response. Necrotic specifically inhibits an extracellular serine proteinase cascade leading to activation of the Toll ligand, Spätzle. Necrotic carries a polyglutamine extension amino-te...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2080852/ https://ncbi.nlm.nih.gov/pubmed/16360948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ibmb.2005.10.004 |
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