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Immune challenge induces N-terminal cleavage of the Drosophila serpin Necrotic

The Drosophila Necrotic protein is a serine proteinase inhibitor, which regulates the Toll-mediated innate immune response. Necrotic specifically inhibits an extracellular serine proteinase cascade leading to activation of the Toll ligand, Spätzle. Necrotic carries a polyglutamine extension amino-te...

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Detalles Bibliográficos
Main Authors: Pelte, Nadège, Robertson, Andrew S., Zou, Zhen, Belorgey, Didier, Dafforn, Timothy R., Jiang, Haobo, Lomas, David, Reichhart, Jean-Marc, Gubb, David
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080852/
https://ncbi.nlm.nih.gov/pubmed/16360948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ibmb.2005.10.004
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