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A serpin mutant links Toll activation to melanization in the host defence of Drosophila

A prominent response during the Drosophila host defence is the induction of proteolytic cascades, some of which lead to localized melanization of pathogen surfaces, while others activate one of the major players in the systemic antimicrobial response, the Toll pathway. Despite the fact that gain-of-...

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Detalhes bibliográficos
Main Authors: Ligoxygakis, Petros, Pelte, Nadège, Ji, Chuanyi, Leclerc, Vincent, Duvic, Bernard, Belvin, Marcia, Jiang, Haobo, Hoffmann, Jules A., Reichhart, Jean-Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136964/
https://ncbi.nlm.nih.gov/pubmed/12456640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf661
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