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Production of recombinant adeno-associated vectors using two bioreactor configurations at different scales
The conventional methods for producing recombinant adeno-associated virus (rAAV) rely on transient transfection of adherent mammalian cells. To gain acceptance and achieve current good manufacturing process (cGMP) compliance, clinical grade rAAV production process should have the following qualities...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2080829/ https://ncbi.nlm.nih.gov/pubmed/17606302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2007.05.020 |
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