AGE-RELATED INCREASES IN OXIDATIVELY DAMAGED PROTEINS OF MOUSE KIDNEY MITOCHONDRIAL ELECTRON TRANSPORT CHAIN COMPLEXES

Mitochondrial dysfunction generates reactive oxygen species (ROS) which damage essential macromolecules. Oxidative modification of proteins, DNA, and lipids has been implicated as a major causal factor in the age-associated decline in tissue function. Mitochondrial electron transport chain complexes...

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Autors principals: Choksi, Kashyap B., Nuss, Jonathan E., Boylston, William H., Rabek, Jeffrey P., Papaconstantinou, John
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080815/
https://ncbi.nlm.nih.gov/pubmed/17936188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.07.027
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