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AGE-RELATED ALTERATIONS IN OXIDATIVELY DAMAGED PROTEINS OF MOUSE HEART MITOCHONDRIAL ELECTRON TRANSPORT CHAIN COMPLEXES

Mitochondrial generated ROS increases with age and is a major factor that damages proteins by oxidative modification. Accumulation of oxidatively damaged proteins has been implicated as a causal factor in the age-associated decline in tissue function. Mitochondrial electron transport chain (ETC) com...

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Detalhes bibliográficos
Main Authors: Choksi, Kashyap B., Papaconstantinou, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423468/
https://ncbi.nlm.nih.gov/pubmed/18331850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.01.032
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