AGE-RELATED INCREASES IN OXIDATIVELY DAMAGED PROTEINS OF MOUSE KIDNEY MITOCHONDRIAL ELECTRON TRANSPORT CHAIN COMPLEXES

Mitochondrial dysfunction generates reactive oxygen species (ROS) which damage essential macromolecules. Oxidative modification of proteins, DNA, and lipids has been implicated as a major causal factor in the age-associated decline in tissue function. Mitochondrial electron transport chain complexes...

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Detalhes bibliográficos
Main Authors: Choksi, Kashyap B., Nuss, Jonathan E., Boylston, William H., Rabek, Jeffrey P., Papaconstantinou, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080815/
https://ncbi.nlm.nih.gov/pubmed/17936188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.07.027
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