A carregar...

C1q deficiency promotes the production of transgenic-derived IgM and IgG3 autoantibodies in anti-DNA knock-in transgenic mice

C1q-deficient mice have been shown to develop a lupus-like disease and to display an impaired clearance of apoptotic cells that are enriched in lupus autoantigens. However, the role of C1q in the regulation of autoreactive B cells remains debatable. To explore this we crossed MRL/Mp C1q-deficient mi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Fossati-Jimack, Liliane, Cortes-Hernandez, Josefina, Norsworthy, Peter J., Walport, Mark J., Cook, H. Terence, Botto, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: Pergamon Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080686/
https://ncbi.nlm.nih.gov/pubmed/17675234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2007.06.162
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!