Regulation of B cell tolerance by 129-derived chromosome 1 loci in C57BL/6 mice

OBJECTIVE: Systemic lupus erythematosus is a multifactorial disease with a strong genetic component. Previous studies have shown that a 129-derived chromosome 1 interval (Sle16) on the C57BL/6 (B6) background is sufficient to induce humoral autoimmunity. The aim of the present study was to elucidate...

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Detalhes bibliográficos
Main Authors: Fossati-Jimack, Liliane, Cortes-Hernandez, Josefina, Norsworthy, Peter J, Cook, H Terence, Walport, Mark J, Botto, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2008
Assuntos:
Systemic Lupus Erythematosus Basic Science Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658014/
https://ncbi.nlm.nih.gov/pubmed/18576325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23553
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