Alternately spliced WT1 antisense transcripts interact with WT1 sense RNA and show epigenetic and splicing defects in cancer

Many mammalian genes contain overlapping antisense RNAs, but the functions and mechanisms of action of these transcripts are mostly unknown. WT1 is a well-characterized developmental gene that is mutated in Wilms’ tumor (WT) and acute myeloid leukaemia (AML) and has an antisense transcript (WT1-AS),...

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Detaylı Bibliyografya
Asıl Yazarlar: Dallosso, Anthony R., Hancock, Anne L., Malik, Sally, Salpekar, Ashreena, King-Underwood, Linda, Pritchard-Jones, Kathy, Peters, Jo, Moorwood, Kim, Ward, Andrew, Malik, Karim T.A., Brown, Keith W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2007
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080606/
https://ncbi.nlm.nih.gov/pubmed/17940140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.562907
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