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Substrate modulation of enzyme activity in the herpesvirus protease family
The herpesvirus proteases are an example in which allosteric regulation of an enzyme activity is achieved through the formation of quaternary structure. Here, we report a 1.7 Å resolution structure of Kaposi’s Sarcoma herpesvirus protease in complex with a hexapeptide transition state analogue that...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2078331/ https://ncbi.nlm.nih.gov/pubmed/17870089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.07.073 |
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