Direct antidiabetic effect of leptin through triglyceride depletion of tissues

Leptin is currently believed to control body composition largely, if not entirely, via hypothalamic receptors that regulate food intake and thermogenesis. Here we demonstrate direct extraneural effects of leptin to deplete fat content of both adipocytes and nonadipocytes to levels far below those of...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Shimabukuro, Michio, Koyama, Kazunori, Chen, Guoxun, Wang, May-Yun, Trieu, Falguni, Lee, Young, Newgard, Christopher B., Unger, Roger H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20776/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9114043/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.9.4637
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