Direct antidiabetic effect of leptin through triglyceride depletion of tissues

Leptin is currently believed to control body composition largely, if not entirely, via hypothalamic receptors that regulate food intake and thermogenesis. Here we demonstrate direct extraneural effects of leptin to deplete fat content of both adipocytes and nonadipocytes to levels far below those of...

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Главные авторы: Shimabukuro, Michio, Koyama, Kazunori, Chen, Guoxun, Wang, May-Yun, Trieu, Falguni, Lee, Young, Newgard, Christopher B., Unger, Roger H.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences of the USA 1997
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC20776/
https://ncbi.nlm.nih.gov/pubmed/9114043
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