Direct antidiabetic effect of leptin through triglyceride depletion of tissues

Leptin is currently believed to control body composition largely, if not entirely, via hypothalamic receptors that regulate food intake and thermogenesis. Here we demonstrate direct extraneural effects of leptin to deplete fat content of both adipocytes and nonadipocytes to levels far below those of...

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Autors principals: Shimabukuro, Michio, Koyama, Kazunori, Chen, Guoxun, Wang, May-Yun, Trieu, Falguni, Lee, Young, Newgard, Christopher B., Unger, Roger H.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC20776/
https://ncbi.nlm.nih.gov/pubmed/9114043
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