CDDO induces granulocytic differentiation of myeloid leukemic blasts through translational up-regulation of p42 CCAAT enhancer–binding protein alpha

2-Cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) induces differentiation and apoptosis of tumor cells in vitro and in vivo. Here we assessed the effects of CDDO on CCAAT enhancer–binding protein alpha (CEBPA), a transcription factor critical for granulocytic differentiation. In HL60 acute myeloi...

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Detaylı Bibliyografya
Asıl Yazarlar: Koschmieder, Steffen, D'Alò, Francesco, Radomska, Hanna, Schöneich, Christine, Chang, Ji Suk, Konopleva, Marina, Kobayashi, Susumu, Levantini, Elena, Suh, Nanjoo, Di Ruscio, Annalisa, Voso, Maria Teresa, Watt, Julie C., Santhanam, Ramasamy, Sargin, Bülent, Kantarjian, Hagop, Andreeff, Michael, Sporn, Michael B., Perrotti, Danilo, Berdel, Wolfgang E., Müller-Tidow, Carsten, Serve, Hubert, Tenen, Daniel G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2007
Konular:
Neoplasia
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077317/
https://ncbi.nlm.nih.gov/pubmed/17671235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-11-058941
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