CCAAT/Enhancer Binding Protein α Is a Regulatory Switch Sufficient for Induction of Granulocytic Development from Bipotential Myeloid Progenitors

Míreanna Comhchosúla

• Absence of the transcription factor CCAAT enhancer binding protein α results in loss of myeloid identity in bcr/abl-induced malignancy
  le: Wagner, Katharina, et al.
  Foilsithe: (2006)
• CDDO induces granulocytic differentiation of myeloid leukemic blasts through translational up-regulation of p42 CCAAT enhancer–binding protein alpha
  le: Koschmieder, Steffen, et al.
  Foilsithe: (2007)
• CCAAT/enhancer binding protein ɛ is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing
  le: Yamanaka, Ryuya, et al.
  Foilsithe: (1997)
• Wnt signaling and tbx16 form a bistable switch to commit bipotential progenitors to mesoderm
  le: Bouldin, Cortney M., et al.
  Foilsithe: (2015)
• Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein α-deficient mice
  le: Zhang, Dong-Er, et al.
  Foilsithe: (1997)