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CCAAT/Enhancer Binding Protein α Is a Regulatory Switch Sufficient for Induction of Granulocytic Development from Bipotential Myeloid Progenitors

The transcription factor CCAAT/enhancer binding protein α (C/EBPα) regulates a number of myeloid cell-specific genes. To delineate the role of C/EBPα in human granulopoiesis, we studied its expression and function in human primary cells and bipotential (granulocytic/monocytic) myeloid cell lines. We...

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Detalhes bibliográficos
Main Authors: Radomska, Hanna S., Huettner, Claudia S., Zhang, Pu, Cheng, Tao, Scadden, David T., Tenen, Daniel G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109014/
https://ncbi.nlm.nih.gov/pubmed/9632814
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