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Human G(sα) mutant causes pseudohypoparathyroidism type Ia/neonatal diarrhea, a potential cell-specific role of the palmitoylation cycle

Pseudohypoparathyroidism type Ia (PHP-Ia) results from the loss of one allele of G(sα), causing resistance to parathyroid hormone and other hormones that transduce signals via G(s). Most G(sα)mutations cause the complete loss of protein expression, but some cause loss of function only, and these hav...

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Main Authors: Makita, Noriko, Sato, Junichiro, Rondard, Philippe, Fukamachi, Hiroshi, Yuasa, Yasuhito, Aldred, Micheala A., Hashimoto, Makiko, Fujita, Toshiro, Iiri, Taroh
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077272/
https://ncbi.nlm.nih.gov/pubmed/17962410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708561104
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