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Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action

Quadruplex ligands are often considered as telomerase inhibitors. Given the fact that some of these molecules are present in the clinical setting, it is important to establish the validity of this assertion. To analyze the effects of these compounds, we used a direct assay with telomerase-enriched e...

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Bibliographische Detailangaben
Hauptverfasser: De Cian, Anne, Cristofari, Gael, Reichenbach, Patrick, De Lemos, Elsa, Monchaud, David, Teulade-Fichou, Marie-Paule, Shin-ya, Kazuo, Lacroix, Laurent, Lingner, Joachim, Mergny, Jean-Louis
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077259/
https://ncbi.nlm.nih.gov/pubmed/17954919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707365104
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