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Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action

Quadruplex ligands are often considered as telomerase inhibitors. Given the fact that some of these molecules are present in the clinical setting, it is important to establish the validity of this assertion. To analyze the effects of these compounds, we used a direct assay with telomerase-enriched e...

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Detalhes bibliográficos
Main Authors: De Cian, Anne, Cristofari, Gael, Reichenbach, Patrick, De Lemos, Elsa, Monchaud, David, Teulade-Fichou, Marie-Paule, Shin-ya, Kazuo, Lacroix, Laurent, Lingner, Joachim, Mergny, Jean-Louis
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077259/
https://ncbi.nlm.nih.gov/pubmed/17954919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707365104
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