Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action

Quadruplex ligands are often considered as telomerase inhibitors. Given the fact that some of these molecules are present in the clinical setting, it is important to establish the validity of this assertion. To analyze the effects of these compounds, we used a direct assay with telomerase-enriched e...

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Detaylı Bibliyografya
Asıl Yazarlar: De Cian, Anne, Cristofari, Gael, Reichenbach, Patrick, De Lemos, Elsa, Monchaud, David, Teulade-Fichou, Marie-Paule, Shin-ya, Kazuo, Lacroix, Laurent, Lingner, Joachim, Mergny, Jean-Louis
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2007
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077259/
https://ncbi.nlm.nih.gov/pubmed/17954919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707365104
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