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Identifying the subproteome of kinetically stable proteins via diagonal 2D SDS/PAGE

Most proteins are in equilibrium with partially and globally unfolded conformations. In contrast, kinetically stable proteins (KSPs) are trapped by an energy barrier in a specific state, unable to transiently sample other conformations. Among many potential roles, it appears that kinetic stability (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xia, Ke, Manning, Marta, Hesham, Helai, Lin, Qishan, Bystroff, Christopher, Colón, Wilfredo
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077256/
https://ncbi.nlm.nih.gov/pubmed/17956990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705417104
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