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Crystal structure of human intrinsic factor: Cobalamin complex at 2.6-Å resolution
The structure of intrinsic factor (IF) in complex with cobalamin (Cbl) was determined at 2.6-Å resolution. The overall fold of the molecule is that of an α(6)/α(6) barrel. It is a two-domain protein, and the Cbl is bound at the interface of the domains in a base-on conformation. Surprisingly, two fu...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2077253/ https://ncbi.nlm.nih.gov/pubmed/17954916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703228104 |
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