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Insight into the mechanism of biological methanol activation based on the crystal structure of the methanol-cobalamin methyltransferase complex

Some methanogenic and acetogenic microorganisms have the catalytic capability to cleave heterolytically the C [Image: see text] O bond of methanol. To obtain insight into the elusive enzymatic mechanism of this challenging chemical reaction we have investigated the methanol-activating MtaBC complex...

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Detalhes bibliográficos
Main Authors: Hagemeier, Christoph H., Kr̈er, Markus, Thauer, Rudolf K., Warkentin, Eberhard, Ermler, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1748152/
https://ncbi.nlm.nih.gov/pubmed/17142327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603650103
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