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Structure of the acetophenone carboxylase core complex: prototype of a new class of ATP-dependent carboxylases/hydrolases

Degradation of the aromatic ketone acetophenone is initiated by its carboxylation to benzoylacetate catalyzed by acetophenone carboxylase (Apc) in a reaction dependent on the hydrolysis of two ATP to ADP and P(i). Apc is a large protein complex which dissociates during purification into a heteroocta...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Weidenweber, Sina, Schühle, Karola, Demmer, Ulrike, Warkentin, Eberhard, Ermler, Ulrich, Heider, Johann
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214803/
https://ncbi.nlm.nih.gov/pubmed/28054554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39674
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