Chk1 Kinase Negatively Regulates Mitotic Function of Cdc25A Phosphatase through 14-3-3 Binding

The order and fidelity of cell cycle events in mammals is intimately linked to the integrity of the Chk1 kinase-Cdc25A phosphatase pathway. Chk1 phosphorylation targets Cdc25A for destruction and, as shown here, inhibits interactions between Cdc25A and its mitotic substrate cyclin B1-Cdk1. Phosphory...

Volledige beschrijving

Bibliografische gegevens

Gepubliceerd in:	Mol Cell Biol
Hoofdauteurs:	Chen, Mei-Shya, Ryan, Christine E., Piwnica-Worms, Helen
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Taylor & Francis 2003
Onderwerpen:	Cell Growth and Development
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207598/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14559997/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.21.7488-7497.2003
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!