Multistage designs for phase II clinical trials: statistical issues in cancer research.

The main objective of phase II clinical trials is to estimate treatment efficacy on a relatively small number of patients in order to decide whether the treatment ought to be studied in large-scale comparative trials. They play a key role in the drug development process, since the results determine...

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Bibliographic Details
Main Authors: Kramar, A., Potvin, D., Hill, C.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075945/
https://ncbi.nlm.nih.gov/pubmed/8883425
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