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Inosine-Containing dsRNA Binds a Stress-Granule-like Complex and Downregulates Gene Expression In trans

Long double-stranded RNAs (dsRNAs) may undergo extensive modification (hyperediting) by adenosine deaminases that act on RNA (ADARs), where up to 50% of adenosine (A) residues are changed to inosine (I). Traditionally, consequences of A-to-I editing were thought to be limited to modified RNA itself....

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Detalhes bibliográficos
Autor principal: Scadden, A.D.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075533/
https://ncbi.nlm.nih.gov/pubmed/17996712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.09.005
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