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Removal of phosphorylation sites of γ subunit of phosphodiesterase 6 alters rod light response

The phosphodiesterase 6 γ (PDE6γ) inhibitory subunit of the rod PDE6 effector enzyme plays a central role in the turning on and off of the visual transduction cascade, since binding of PDE6γ to the transducin α subunit (Tα) initiates the hydrolysis of the second messenger cGMP, and PDE6γ in associat...

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Bibliografske podrobnosti
Main Authors: Tsang, S H, Woodruff, M L, Janisch, Kerstin M, Cilluffo, M C, Farber, D B, Fain, G L
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075409/
https://ncbi.nlm.nih.gov/pubmed/17138607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.121772
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