Diverse Kir modulators act in close proximity to residues implicated in phosphoinositide binding

Inwardly rectifying potassium (Kir) channels were the first shown to be directly activated by phosphoinositides in general and phosphatidylinositol bisphosphate (PIP(2)) in particular. Atomic resolution structures have been determined for several mammalian and bacterial Kir channels. Basic residues,...

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Bibliographic Details
Main Authors: Logothetis, Diomedes E, Lupyan, Dmitry, Rosenhouse-Dantsker, Avia
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2007
Subjects:
Symposium Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075264/
https://ncbi.nlm.nih.gov/pubmed/17495041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.133157
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