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Diverse Kir modulators act in close proximity to residues implicated in phosphoinositide binding
Inwardly rectifying potassium (Kir) channels were the first shown to be directly activated by phosphoinositides in general and phosphatidylinositol bisphosphate (PIP(2)) in particular. Atomic resolution structures have been determined for several mammalian and bacterial Kir channels. Basic residues,...
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Main Authors: | , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
Blackwell Science Inc
2007
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2075264/ https://ncbi.nlm.nih.gov/pubmed/17495041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.133157 |
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