Mechanisms of ventricular arrhythmogenesis in mice following targeted disruption of KCNE1 modelling long QT syndrome 5

Mutations within KCNE1 encoding a transmembrane protein which coassembles with K(+) channels mediating slow K(+), I(Ks), currents are implicated in cardiac action potential prolongation and ventricular arrhythmogenicity in long QT syndrome 5. We demonstrate the following potentially arrhythmogenic f...

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Main Authors: Thomas, Glyn, Killeen, Matthew J, Gurung, Iman S, Hakim, Parvez, Balasubramaniam, Richard, Goddard, Catharine A, Grace, Andrew A, Huang, Christopher L-H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075126/
https://ncbi.nlm.nih.gov/pubmed/17095567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.118133
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