Modulation of bryostatin 1 muscle toxicity by nifedipine: effects on muscle metabolism and oxygen supply.

Bryostatin 1, an anti-neoplastic agent and protein kinase C activator, has dose-limiting toxicity manifesting as myalgia. Studies in vivo have suggested that this myalgia may be caused by impairment of oxidative metabolism as mitochondrial capacity, muscle reoxygenation and proton washout from muscl...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Thompson, C. H., Macaulay, V. M., O'Byrne, K. J., Kemp, G. J., Wilner, S. M., Talbot, D. C., Harris, A. L., Radda, G. K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 1996
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074524/
https://ncbi.nlm.nih.gov/pubmed/8630272
Tagiau: Ychwanegu Tag
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