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Nifedipine improves blood flow and oxygen supply, but not steady-state oxygenation of tumours in perfusion pressure-controlled isolated limb perfusion

Isolated limb perfusion allows the direct application of therapeutic agents to a tumour-bearing extremity. The present study investigated whether the dihydropyridine-type Ca(2+)-channel blocker nifedipine could improve blood flow and oxygenation status of experimental tumours during isolated limb pe...

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Detalhes bibliográficos
Main Authors: Thews, O, Hummel, M, Kelleher, D K, Lecher, B, Vaupel, P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376281/
https://ncbi.nlm.nih.gov/pubmed/12454778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600611
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