Expression of Mad, an antagonist of Myc oncoprotein function, in differentiating keratinocytes during tumorigenesis of the skin.

The Myc oncoprotein is associated with cell proliferation and is often down-regulated during cell differentiation. The related Mad transcription factor, which antagonises Myc activity, is highly expressed in epidermal keratinocytes. Mad also inhibits cell proliferation in vitro. To study Mad express...

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Autors principals: Lymboussaki, A., Kaipainen, A., Hatva, E., Västrik, I., Jeskanen, L., Jalkanen, M., Werner, S., Stenbäck, F., Alitalo, R.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074494/
https://ncbi.nlm.nih.gov/pubmed/8645578
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