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Modulation of T-lymphocyte development, growth and cell size by the Myc antagonist and transcriptional repressor Mad1

Activated lymphocytes must increase in size and duplicate their contents (cell growth) before they can divide. The molecular events that control cell growth in proliferating lymphocytes and other metazoan cells are still unclear. Here, we utilized transgenesis to provide evidence suggesting that the...

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Main Authors: Iritani, Brian M., Delrow, Jeffrey, Grandori, Carla, Gomez, Ivan, Klacking, Meredith, Carlos, Leni Sue, Eisenman, Robert N.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC126288/
https://ncbi.nlm.nih.gov/pubmed/12234922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf492
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