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Inositol hexakisphosphate stimulates non-Ca(2+)-mediated and primes Ca(2+)-mediated exocytosis of insulin by activation of protein kinase C

d-myo-inositol 1,2,3,4,5,6-hexakisphosphate (InsP(6)), formed via complex pathways of inositol phosphate metabolism, composes the main bulk of inositol polyphosphates in the cell. Relatively little is known regarding possible biological functions for InsP(6). We now show that InsP(6) can modulate in...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Efanov, Alexandre M., Zaitsev, Sergei V., Berggren, Per-Olof
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1997
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Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20740/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9114007/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.9.4435
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