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Inositol hexakisphosphate stimulates non-Ca(2+)-mediated and primes Ca(2+)-mediated exocytosis of insulin by activation of protein kinase C

d-myo-inositol 1,2,3,4,5,6-hexakisphosphate (InsP(6)), formed via complex pathways of inositol phosphate metabolism, composes the main bulk of inositol polyphosphates in the cell. Relatively little is known regarding possible biological functions for InsP(6). We now show that InsP(6) can modulate in...

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Bibliografske podrobnosti
Main Authors: Efanov, Alexandre M., Zaitsev, Sergei V., Berggren, Per-Olof
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences of the USA 1997
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC20740/
https://ncbi.nlm.nih.gov/pubmed/9114007
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