Llwytho...

Synthesis and Evaluation of Febrifugine Analogues as Potential Antimalarial Agents

Febrifugine is an alkaloid isolated from Dichroa febrifuga Lour as the active component against Plasmodium falciparum. Strong liver toxicity has precluded febrifugine as a potential clinical drug. In this study novel febrifugine analogues were designed and synthesized. Lower toxicity was achieved by...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhu, Shuren, Meng, Li, Zhang, Quan, Wei, Lai
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2072810/
https://ncbi.nlm.nih.gov/pubmed/16434194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2006.01.009
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