Cytoplasmic sequestration of an O(6)-methylguanine-DNA methyltransferase enhancer binding protein in DNA repair-deficient human cells
O(6)-Methylguanine-DNA methyltransferase (MGMT), an enzyme that repairs adducts at O(6) of guanine in DNA, is a major determinant of susceptibility to simple methylating carcinogens or of tumor response to anticancer chloroethylating drugs. To investigate the mechanisms underlying cellular expressio...
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| Wydane w: | Proc Natl Acad Sci U S A |
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| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
1997
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20725/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9113992/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.9.4348 |
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