Rapid reversal by naloxone of the chronic effects of morphine on rat liver and brain tryptophan metabolism.

The chronic morphine-induced inhibition of rat liver tryptophan pyrrolase activity and the resultant increases in tryptophan availability to the brain and brain 5-hydroxytryptamine (5-HT) synthesis are reversed within 10 min after naloxone administration. The possible involvement of hepatic tryptoph...

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Bibliographic Details
Main Authors: Badawy, A. A., Evans, M.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1981
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071748/
https://ncbi.nlm.nih.gov/pubmed/7296160
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