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Reversal by naloxone of the effects of chronic administration of drugs of dependence on rat liver and brain tryptophan metabolism.

1. Chronic administration of ethanol, morphine, nicotine or phenobarbitone has previously been shown to enhance rat brain 5-hydroxytryptamine (5-HT) synthesis by increasing the availability of circulating tryptophan to the brain secondarily to the NADPH-mediated inhibition of liver tryptophan pyrrol...

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Autors principals: Badawy, A. A., Evans, M., Punjani, N. F.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1981
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071720/
https://ncbi.nlm.nih.gov/pubmed/7198499
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