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Rapid reversal by naloxone of the chronic effects of morphine on rat liver and brain tryptophan metabolism.

The chronic morphine-induced inhibition of rat liver tryptophan pyrrolase activity and the resultant increases in tryptophan availability to the brain and brain 5-hydroxytryptamine (5-HT) synthesis are reversed within 10 min after naloxone administration. The possible involvement of hepatic tryptoph...

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Hlavní autoři: Badawy, A. A., Evans, M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1981
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2071748/
https://ncbi.nlm.nih.gov/pubmed/7296160
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