Excess intracellular concentration of the pSC101 RepA protein interferes with both plasmid DNA replication and partitioning.
RepA, a plasmid-encoded gene product required for pSC101 replication in Escherichia coli, is shown here to inhibit the replication of pSC101 in vivo when overproduced 4- to 20-fold in trans. Unlike plasmids whose replication is prevented by mutations in the repA gene, plasmids prevented from replica...
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| Publicado no: | J Bacteriol |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC206959/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8253672/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.175.24.7834-7841.1993 |
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