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Monosaccharide-induced lipogenesis regulates the human hepatic sex hormone–binding globulin gene

The liver produces plasma sex hormone–binding globulin (SHBG), which transports sex steroids and regulates their access to tissues. In overweight children and adults, low plasma SHBG levels are a biomarker of the metabolic syndrome and its associated pathologies. Here, we showed in transgenic mice a...

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Détails bibliographiques
Auteurs principaux: Selva, David M., Hogeveen, Kevin N., Innis, Sheila M., Hammond, Geoffrey L.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2066187/
https://ncbi.nlm.nih.gov/pubmed/17992261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32249
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