EBV Latent Membrane Protein 1 Activates Akt, NFκB, and Stat3 in B Cell Lymphomas

Latent membrane protein 1 (LMP1) is the major oncoprotein of Epstein-Barr virus (EBV). In transgenic mice, LMP1 promotes increased lymphoma development by 12 mo of age. This study reveals that lymphoma develops in B-1a lymphocytes, a population that is associated with transformation in older mice. T...

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Detalhes bibliográficos
Main Authors: Shair, Kathy H. Y, Bendt, Katherine M, Edwards, Rachel H, Bedford, Elisabeth C, Nielsen, Judith N, Raab-Traub, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2065877/
https://ncbi.nlm.nih.gov/pubmed/17997602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030166
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