NF-κB1 Haploinsufficiency Causing Immunodeficiency and EBV-Driven Lymphoproliferation

PURPOSE: NF-κB signaling is critically important for regulation of both innate and adaptive immune responses. While activation of NF-κB has been implicated in malignancies such as leukemia and lymphoma, loss-of-function mutations affecting different NF-κB pathway components have been shown to cause...

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Detalles Bibliográficos
Publicado en:J Clin Immunol
Main Authors: Boztug, Heidrun, Hirschmugl, Tatjana, Holter, Wolfgang, Lakatos, Karoly, Kager, Leo, Trapin, Doris, Pickl, Winfried, Förster-Waldl, Elisabeth, Boztug, Kaan
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2016
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940442/
https://ncbi.nlm.nih.gov/pubmed/27338827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-016-0306-1
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