Molecular Architecture and Functional Model of the Complete Yeast ESCRT-I Heterotetramer

The Endosomal Sorting Complex Required for Transport-I (ESCRT-I) complex, which is conserved from yeast to humans, directs the lysosomal degradation of ubiquitinated transmembrane proteins and the budding of the HIV virus. Yeast ESCRT-I contains four subunits, Vps23, Vps28, Vps37 and Mvb12. The crys...

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Bibliografiske detaljer
Main Authors: Kostelansky, Michael S., Schluter, Cayetana, Tam, Yuen Yi C., Lee, Sangho, Ghirlando, Rodolfo, Beach, Bridgette, Conibear, Elizabeth, Hurley, James H.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2065850/
https://ncbi.nlm.nih.gov/pubmed/17442384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.03.016
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