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Hybrid structural model of the complete human ESCRT-0 complex

The human Hrs and STAM proteins comprise the ESCRT-0 complex, which sorts ubiquitinated cell surface receptors to lysosomes for degradation. Here we report a model for the complete ESCRT-0 complex based on the crystal structure of the Hrs-STAM core complex, previously solved domain structures, hydro...

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Autores principales: Ren, Xuefeng, Kloer, Daniel P., Kim, Young C., Ghirlando, Rodolfo, Saidi, Layla F., Hummer, Gerhard, Hurley, James H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676576/
https://ncbi.nlm.nih.gov/pubmed/19278655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.01.012
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