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VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargo

VHS (Vps27, Hrs, and STAM) domains occur in ESCRT-0 subunits Hrs and STAM, GGA adapters, and other trafficking proteins. The structure of the STAM VHS domain–ubiquitin complex was solved at 2.6 Å resolution, revealing that determinants for ubiquitin recognition are conserved in nearly all VHS domain...

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Hlavní autoři: Ren, Xuefeng, Hurley, James H
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845278/
https://ncbi.nlm.nih.gov/pubmed/20150893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.6
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