In vivo tumorigenesis by Jaagsiekte sheep retrovirus (JSRV) requires Y590 in Env TM, but not full length orfX open reading frame

Jaagsiekte retrovirus (JSRV) causes ovine pulmonary adenocarcinoma (OPA), a transmissible lung cancer of sheep. The envelope (Env) glycoprotein protein of JSRV functions as a dominant oncoprotein in vitro and in vivo. An SH2 binding domain (YXXM) in the cytoplasmic tail of the JSRV Env is one of the...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Cousens, Chris, Maeda, Naoyoshi, Murgia, Claudio, Dagleish, Mark P., Palmarini, Massimo, Fan, Hung
Formato: Artigo
Idioma:Inglês
Publicado: 2007
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2065845/
https://ncbi.nlm.nih.gov/pubmed/17610928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.06.004
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares