Lung cancer induced in mice by the envelope protein of jaagsiekte sheep retrovirus (JSRV) closely resembles lung cancer in sheep infected with JSRV

BACKGROUND: Jaagsiekte sheep retrovirus (JSRV) causes a lethal lung cancer in sheep and goats. Expression of the JSRV envelope (Env) protein in mouse lung, by using a replication-defective adeno-associated virus type 6 (AAV6) vector, induces tumors resembling those seen in sheep. However, the mouse...

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Detalhes bibliográficos
Main Authors: Wootton, Sarah K, Metzger, Michael J, Hudkins, Kelly L, Alpers, Charles E, York, Denis, DeMartini, James C, Miller, A Dusty
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1764900/
https://ncbi.nlm.nih.gov/pubmed/17177996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-3-94
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