A Phosphatidylinositol 3-Kinase Docking Site in the Cytoplasmic Tail of the Jaagsiekte Sheep Retrovirus Transmembrane Protein Is Essential for Envelope-Induced Transformation of NIH 3T3 Cells

Jaagsiekte sheep retrovirus (JSRV) is the causative agent of a transmissible lung cancer of sheep known as ovine pulmonary carcinoma. Recently, we have found that the expression of the JSRV envelope (Env) is sufficient to transform mouse NIH 3T3 cells in classical transformation assays. To further i...

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Detalhes bibliográficos
Main Authors: Palmarini, Massimo, Maeda, Naoyoshi, Murgia, Claudio, De-Fraja, Claudio, Hofacre, Andrew, Fan, Hung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Transformation and Oncogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114680/
https://ncbi.nlm.nih.gov/pubmed/11602740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.22.11002-11009.2001
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