A Phosphatidylinositol 3-Kinase Docking Site in the Cytoplasmic Tail of the Jaagsiekte Sheep Retrovirus Transmembrane Protein Is Essential for Envelope-Induced Transformation of NIH 3T3 Cells

Jaagsiekte sheep retrovirus (JSRV) is the causative agent of a transmissible lung cancer of sheep known as ovine pulmonary carcinoma. Recently, we have found that the expression of the JSRV envelope (Env) is sufficient to transform mouse NIH 3T3 cells in classical transformation assays. To further i...

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Détails bibliographiques

Publié dans:	J Virol
Auteurs principaux:	Palmarini, Massimo, Maeda, Naoyoshi, Murgia, Claudio, De-Fraja, Claudio, Hofacre, Andrew, Fan, Hung
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2001
Sujets:	Transformation and Oncogenesis
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114680/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11602740/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.22.11002-11009.2001
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