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Inheritance of an Epigenetic Mark: The CpG DNA Methyltransferase 1 Is Required for De Novo Establishment of a Complex Pattern of Non-CpG Methylation

Site-specific methylation of cytosines is a key epigenetic mark of vertebrate DNA. While a majority of the methylated residues are in the symmetrical (meC)pG:Gp(meC) configuration, a smaller, but significant fraction is found in the CpA, CpT and CpC asymmetric (non-CpG) dinucleotides. CpG methylatio...

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Hlavní autoři: Grandjean, Valérie, Yaman, Ruken, Cuzin, François, Rassoulzadegan, Minoo
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2065839/
https://ncbi.nlm.nih.gov/pubmed/17989773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001136
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